BI-2536 Promotes Neuroblastoma Cell Death via Minichromosome Maintenance Complex Components 2 and 10

• Main Authors: Chiao-Hui Hsieh (Author), Hsiang-Ning Yeh (Author), Chen-Tsung Huang (Author), Wei-Hsuan Wang (Author), Wen-Ming Hsu (Author), Hsuan-Cheng Huang (Author), Hsueh-Fen Juan (Author)
• Format: Book
• Published: MDPI AG, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

DNA replication is initiated with the recognition of the starting point of multiple replication forks by the origin recognition complex and activation of the minichromosome maintenance complex 10 (MCM10). Subsequently, DNA helicase, consisting of the MCM protein subunits MCM2-7, unwinds double-stran...