Reduction of monoclonal antibody viscosity using interpretable machine learning

• Główni autorzy: Emily K. Makowski (Autor), Hsin-Ting Chen (Autor), Tiexin Wang (Autor), Lina Wu (Autor), Jie Huang (Autor), Marissa Mock (Autor), Patrick Underhill (Autor), Emma Pelegri-O'Day (Autor), Erick Maglalang (Autor), Dwight Winters (Autor), Peter M. Tessier (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

ABSTRACTEarly identification of antibody candidates with drug-like properties is essential for simplifying the development of safe and effective antibody therapeutics. For subcutaneous administration, it is important to identify candidates with low self-association to enable their formulation at hig...