Reduction of monoclonal antibody viscosity using interpretable machine learning

• Main Authors: Emily K. Makowski (Author), Hsin-Ting Chen (Author), Tiexin Wang (Author), Lina Wu (Author), Jie Huang (Author), Marissa Mock (Author), Patrick Underhill (Author), Emma Pelegri-O'Day (Author), Erick Maglalang (Author), Dwight Winters (Author), Peter M. Tessier (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTEarly identification of antibody candidates with drug-like properties is essential for simplifying the development of safe and effective antibody therapeutics. For subcutaneous administration, it is important to identify candidates with low self-association to enable their formulation at hig...