Reduction of monoclonal antibody viscosity using interpretable machine learning

• Main Authors: Emily K. Makowski (Author), Hsin-Ting Chen (Author), Tiexin Wang (Author), Lina Wu (Author), Jie Huang (Author), Marissa Mock (Author), Patrick Underhill (Author), Emma Pelegri-O'Day (Author), Erick Maglalang (Author), Dwight Winters (Author), Peter M. Tessier (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Fag: article
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ABSTRACTEarly identification of antibody candidates with drug-like properties is essential for simplifying the development of safe and effective antibody therapeutics. For subcutaneous administration, it is important to identify candidates with low self-association to enable their formulation at hig...