Sarecycline Demonstrated Reduced Activity Compared to Minocycline against Microbial Species Representing Human Gastrointestinal Microbiota

• Main Authors: Mahmoud A. Ghannoum (Author), Lisa Long (Author), Christopher G. Bunick (Author), James Q. Del Rosso (Author), Ahmed Gamal (Author), Stephen K. Tyring (Author), Thomas S. McCormick (Author), Ayman Grada (Author)
• Format: Book
• Published: MDPI AG, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prolonged use of broad-spectrum tetracycline antibiotics such as minocycline and doxycycline may significantly alter the gut and skin microbiome leading to dysbiosis. Sarecycline, a narrow-spectrum tetracycline-class antibiotic used for acne treatment, is hypothesized to have minimal impact on the g...