Delivery of Protein Kinase A by CRISPRMAX and Its Effects on Breast Cancer Stem-Like Properties

• Main Authors: Jun-Nian Zhou (Author), Tzu-Chen Rautio (Author), Chang Liu (Author), Xiao-Yu Xu (Author), Dong-Qing Wang (Author), Yong Guo (Author), John Eriksson (Author), Hongbo Zhang (Author)
• Format: Book
• Published: MDPI AG, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Protein kinase A (PKA) activation has recently been reported to inhibit epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) ability, which is considered to be responsible for chemoresistance and tumor recurrence in patients. While current studies mainly focus on gene manipulation of t...