Delivery of Protein Kinase A by CRISPRMAX and Its Effects on Breast Cancer Stem-Like Properties

• المؤلفون الرئيسيون: Jun-Nian Zhou (مؤلف), Tzu-Chen Rautio (مؤلف), Chang Liu (مؤلف), Xiao-Yu Xu (مؤلف), Dong-Qing Wang (مؤلف), Yong Guo (مؤلف), John Eriksson (مؤلف), Hongbo Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2020-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Protein kinase A (PKA) activation has recently been reported to inhibit epithelial-mesenchymal transition (EMT) and cancer stem cell (CSC) ability, which is considered to be responsible for chemoresistance and tumor recurrence in patients. While current studies mainly focus on gene manipulation of t...