Mesenchymal Stem Cells Engineered by Nonviral Vectors: A Powerful Tool in Cancer Gene Therapy

• Glavni autori: Yuan Ding (Autor), Chenyang Wang (Autor), Zhongquan Sun (Autor), Yingsheng Wu (Autor), Wanlu You (Autor), Zhengwei Mao (Autor), Weilin Wang (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-06-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Due to their "tumor homing" and "immune privilege" characteristics, the use of mesenchymal stem cells (MSCs) has been proposed as a novel tool against cancer. MSCs are genetically engineered in vitro and then utilized to deliver tumoricidal agents, including prodrugs and bioactiv...