Impaired Pharmacokinetics of Amiodarone under Veno-Venous Extracorporeal Membrane Oxygenation: From Bench to Bedside

• Main Authors: Mickaël Lescroart (Author), Claire Pressiat (Author), Benjamin Péquignot (Author), N'Guyen Tran (Author), Jean-Louis Hébert (Author), Nassib Alsagheer (Author), Nicolas Gambier (Author), Bijan Ghaleh (Author), Julien Scala-Bertola (Author), Bruno Levy (Author)
• Format: Book
• Published: MDPI AG, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Adjusting drug therapy under veno-venous extracorporeal membrane oxygenation (VV ECMO) is challenging. Although impaired pharmacokinetics (PK) under VV ECMO have been reported for sedative drugs and antibiotics, data about amiodarone are lacking. We evaluated the pharmacokinetics of amio...