Simple improvements in vector design afford substantial gains in AAV delivery of aggregation-slowing Aβ variants

Adeno-associated virus (AAV) gene therapy for neurological disease has gained traction due to stunning advances in capsid evolution for CNS targeting. With AAV brain delivery now in focus, conventional improvements in viral expression vectors offer a complementary route for optimizing gene delivery....

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Bibliographic Details
Main Authors: Ella Borgenheimer (Author), Cameron Trueblood (Author), Bryan L. Nguyen (Author), William R. Lagor (Author), Joanna L. Jankowsky (Author)
Format: Book
Published: Elsevier, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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