A Transcriptomic Biomarker Predicting Linezolid-Associated Neuropathy During Treatment of Drug-Resistant Tuberculosis

• मुख्य लेखकों: Nika Zielinski (लेखक), Dragos Baiceanu (लेखक), Antonela Dragomir (लेखक), Jan Heyckendorf (लेखक), Elmira Ibraim (लेखक), Niklas Köhler (लेखक), Christoph Leschczyk (लेखक), Cristina Popa (लेखक), Andrea Rachow (लेखक), Jens Sachsenweger (लेखक), Patricia Carballo (लेखक), Dagmar Schaub (लेखक), Hajo Zeeb (लेखक), Begna Tulu (लेखक), Andrew DiNardo (लेखक), Christoph Lange (लेखक), Maja Reimann (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Case Western Reserve University, 2024-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Neuropathic adverse events occur frequently in linezolid-containing regimens, some of which remain irreversible after drug discontinuation. Objective: We aimed to identify and validate a host RNA-based biomarker that can predict linezolid-associated neuropathy before multidrug-resistant/...