Nanocarrier Lipid Composition Modulates the Impact of Pulmonary Surfactant Protein B (SP-B) on Cellular Delivery of siRNA

• Hoofdauteurs: Roberta Guagliardo (Auteur), Pieterjan Merckx (Auteur), Agata Zamborlin (Auteur), Lynn De Backer (Auteur), Mercedes Echaide (Auteur), Jesus Pérez-Gil (Auteur), Stefaan C. De Smedt (Auteur), Koen Raemdonck (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2019-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Two decades since the discovery of the RNA interference (RNAi) pathway, we are now witnessing the approval of the first RNAi-based treatments with small interfering RNA (siRNA) drugs. Nevertheless, the widespread use of siRNA is limited by various extra- and intracellular barriers, requiring its enc...