Clinical Utility of Confirmatory Genetic Testing to Differentiate Sickle Cell Trait from Sickle-β⁺-Thalassemia by Newborn Screening

• Asıl Yazarlar: Lisa M. Shook (Yazar), Deidra Haygood (Yazar), Charles T. Quinn (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Hemoglobin separation techniques are the most commonly used laboratory methods in newborn screening and confirmatory testing programs for hemoglobinopathies. However, such protein-based testing cannot accurately detect several hemoglobinopathies in newborns, especially when β-thalassemia mutations a...