A new and simple non-chromatographic method for isolation of drug/linker constructs: vc-MMAE evaluation

• প্রধান লেখক: Meghdad Abdollahpour-Alitappeh (লেখক), Mahdi Habibi-Anbouhi (লেখক), Saeed Balalaie (লেখক), Farhad Golmohammadi (লেখক), Majid Lotfinia (লেখক), Mohsen Abolhassani (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Shahrekord University of Medical Sciences, 2017-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Introduction: Auristatin and its derivatives (synthetic analogues of dolastatin 10, an antineoplastic natural product), are highly potent antimitotic agents which have attracted considerable attention because of their cytotoxic activity when targeting tumor cells in the form of antibody-drug conjuga...