Synthesis and evaluation of the antifungal activity of 5-hydroxy-3-phenyl-1H-pyrazole-1-carbothioamide for use in the oral environment

• Main Authors: Hossein Amin Zadeh (Author), Ali Asghar Zomorodkia (Author), Saeid Hadi (Author), Iman Mohammad Zadeh (Author), Seyed Abd Alreza Sabetghadam (Author), Vahid Hadi (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aim: Candida albicans and Candida tropicalis, can cause superficial infections of the oral mucosa as well as disseminated bloodstream and deep-tissue infections. The most frequently employed class of antifungals used for Candida infection treatment are the azole antifungals. Their low...