CD39 and immune regulation in a chronic helminth infection: The puzzling case of Mansonella ozzardi.

• Main Authors: Nathália F Lima (Author), Raquel M Gonçalves-Lopes (Author), Yvonne C M Kruize (Author), Maria Yazdanbakhsh (Author), Marcelo U Ferreira (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic helminth infections typically induce an immunoregulatory environment, with markedly reduced immune responses to both parasite-specific and unrelated bystander antigens. Here we tested whether these changes are also observed in human infections with Mansonella ozzardi, a neglected filarial ne...