Dose-Dependent Effect of Melatonin on BAT Thermogenesis in Zücker Diabetic Fatty Rat: Future Clinical Implications for Obesity

• Main Authors: Samira Aouichat (Author), Enrique Raya (Author), Antonio Molina-Carballo (Author), Antonio Munoz-Hoyos (Author), Abdelkarim Saleh Aloweidi (Author), Ehab Kotb Elmahallawy (Author), Ahmad Agil (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Experimental data have revealed that melatonin at high doses reduced obesity and improved metabolic outcomes in experimental models of obesity, mainly by enhancing brown adipose tissue (BAT) thermogenesis. A potential dose-response relationship has yet to be performed to translate these promising fi...