Inhibition of Hepatitis B Virus (HBV) by Tachyplesin, a Marine Antimicrobial Cell-Penetrating Peptide

• Autori principali: Pankhuri Narula (Autore), Sankar Kiruthika (Autore), Shruti Chowdhari (Autore), Perumal Vivekanandan (Autore), Archana Chugh (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-02-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

We investigate the role of Tachyplesin (Tpl), a marine antimicrobial cell-penetrating peptide, as an anti-HBV agent. Our findings, using confocal microscopy and flow cytometry, demonstrate the internalization of FITC-Tpl in both Huh7 and HepG2 cell lines. Further, our results show that Tpl inhibits...