Inhibition of Hepatitis B Virus (HBV) by Tachyplesin, a Marine Antimicrobial Cell-Penetrating Peptide

• Principais autores: Pankhuri Narula (Autor), Sankar Kiruthika (Autor), Shruti Chowdhari (Autor), Perumal Vivekanandan (Autor), Archana Chugh (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

We investigate the role of Tachyplesin (Tpl), a marine antimicrobial cell-penetrating peptide, as an anti-HBV agent. Our findings, using confocal microscopy and flow cytometry, demonstrate the internalization of FITC-Tpl in both Huh7 and HepG2 cell lines. Further, our results show that Tpl inhibits...