Influence of a 3' Terminal Ribozyme on AgoshRNA Biogenesis and Activity
Short hairpin RNAs (shRNAs) can induce gene silencing via the RNA interference (RNAi) mechanism. We designed an alternative shRNA molecule with a relatively short base-paired stem that bypasses Dicer and instead is processed by the Argonaute 2 (Ago2) protein into a single guide RNA strand that effec...
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Format: | Book |
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Elsevier,
2019-06-01T00:00:00Z.
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A1234.567 |
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Copy 1 | Available |