Echis carinatus snake venom metalloprotease-induced toxicities in mice: Therapeutic intervention by a repurposed drug, Tetraethyl thiuram disulfide (Disulfiram).

• Main Authors: Gotravalli V Rudresha (Author), Amog P Urs (Author), Vaddarahally N Manjuprasanna (Author), Mallanayakanakatte D Milan Gowda (Author), Krishnegowda Jayachandra (Author), Rajesh Rajaiah (Author), Bannikuppe S Vishwanath (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Echis carinatus (EC) is known as saw-scaled viper and it is endemic to the Indian subcontinent. Envenoming by EC represents a major cause of snakebite mortality and morbidity in the Indian subcontinent. Zinc (Zn++) dependent snake venom metalloproteases (SVMPs) present in Echis carinatus venom (ECV)...