Improved Anticancer Activities of a New Pentafluorothio-Substituted Vorinostat-Type Histone Deacetylase Inhibitor

• 主要な著者: Nils Goehringer (著者), Yayi Peng (著者), Bianca Nitzsche (著者), Hannah Biermann (著者), Rohan Pradhan (著者), Rainer Schobert (著者), Marco Herling (著者), Michael Höpfner (著者), Bernhard Biersack (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The development of new anticancer drugs is necessary in order deal with the disease and with the drawbacks of currently applied drugs. Epigenetic dysregulations are a central hallmark of cancerogenesis and histone deacetylases (HDACs) emerged as promising anticancer targets. HDAC inhibitors are prom...