Metformin regulates the Th17/Treg balance by glycolysis with TIGAR in hepatic ischemia-reperfusion injury
The balance of Th17/Treg plays an important role in hepatic ischemia-reperfusion (I/R) injury. Glycolysis and glutaminolysis for energy metabolism governs the differentiate of CD 4+ T-cells to Th17/Treg. Metformin can regulate glucose metabolism in the liver, but its protective effect on I/R liver i...
Saved in:
Main Authors: | Aiwen Jiang (Author), Peishan Du (Author), Yunning Liu (Author), Jiekun Pu (Author), Jinzheng Shi (Author), Heming Zhang (Author) |
---|---|
Format: | Book |
Published: |
Elsevier,
2021-05-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Metformin Attenuates Experimental Autoimmune Arthritis through Reciprocal Regulation of Th17/Treg Balance and Osteoclastogenesis
by: Hye-Jin Son, et al.
Published: (2014) -
Th17 and Treg Balance in Children With Obesity and Metabolically Altered Status
by: Valeria Calcaterra, et al.
Published: (2020) -
Metabolic regulation of the Th17/Treg balance in inflammatory bowel disease
by: Shunfen Zhang, et al.
Published: (2024) -
Intrahepatic TH17/TReg Cells in Homeostasis and Disease-It's All About the Balance
by: Hannah K. Drescher, et al.
Published: (2020) -
Qingjie Fuzheng granules treat ulcerative colitis by regulating Th17/Treg balance
by: Hangyan Zhong, et al.
Published: (2024)