Zika viruses of African and Asian lineages cause fetal harm in a mouse model of vertical transmission.

• Main Authors: Anna S Jaeger (Author), Reyes A Murrieta (Author), Lea R Goren (Author), Chelsea M Crooks (Author), Ryan V Moriarty (Author), Andrea M Weiler (Author), Sierra Rybarczyk (Author), Matthew R Semler (Author), Christopher Huffman (Author), Andres Mejia (Author), Heather A Simmons (Author), Michael Fritsch (Author), Jorge E Osorio (Author), Jens C Eickhoff (Author), Shelby L O'Connor (Author), Gregory D Ebel (Author), Thomas C Friedrich (Author), Matthew T Aliota (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Congenital Zika virus (ZIKV) infection was first linked to birth defects during the American outbreak in 2015/2016. It has been proposed that mutations unique to the Asian/American-genotype explain, at least in part, the ability of Asian/American ZIKV to cause congenital Zika syndrome (CZS). Recent...