Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice

• Asıl Yazarlar: Santhosh Karanth (Yazar), Vy My Tran (Yazar), Balagurunathan Kuberan (Yazar), Amnon Schlegel (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2013-11-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

SUMMARY Lipid disorders pose therapeutic challenges. Previously we discovered that mutation of the hepatocyte β-hydroxybutyrate transporter Slc16a6a in zebrafish causes hepatic steatosis during fasting, marked by increased hepatic triacylglycerol, but not cholesterol. This selective diversion of tra...