Sonic Hedgehog receptor Patched deficiency in astrocytes enhances glucose metabolism in mice

• Main Authors: Linda Tirou (Author), Mariagiovanna Russo (Author), Helene Faure (Author), Giuliana Pellegrino (Author), Clement Demongin (Author), Mathieu Daynac (Author), Ariane Sharif (Author), Jeremy Amosse (Author), Soazig Le Lay (Author), Raphaël Denis (Author), Serge Luquet (Author), Mohammed Taouis (Author), Yacir Benomar (Author), Martial Ruat (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Astrocytes are glial cells proposed as the main Sonic hedgehog (Shh)-responsive cells in the adult brain. Their roles in mediating Shh functions are still poorly understood. In the hypothalamus, astrocytes support neuronal circuits implicated in the regulation of energy metabolism. In thi...