Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression

• Main Authors: Yuao Deng (Author), Fang Zhao (Author), Liu Hui (Author), Xiuyun Li (Author), Danyu Zhang (Author), Wang Lin (Author), Zhiqiang Chen (Author), Yingxia Ning (Author)
• Formato: Livro
• Publicado em: BMC, 2017-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Discoidin Domain Receptor 1 (DDR1) belongs to the family of collagen receptor tyrosine kinases that confers the progression of various cancers. Aberrant expression of DDR1 was detected in several human cancers including ovarian cancer, which had been shown to increase the migrati...