Effect of Sedum sarmentosum Bunge Extract on Aristolochic Acid- Induced Renal Tubular Epithelial Cell Injury

• Main Authors: Yongheng Bai (Author), Hong Lu (Author), Liping Hu (Author), Dan Hong (Author), Linchao Ding (Author), Bicheng Chen (Author)
• Format: Book
• Published: Elsevier, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aristolochic acid (AA) is known as a potent mutagen that induces significant cytotoxic and mutagenic effects on renal tubular epithelial cells. Clinically, the persistent injury of AA results in the infiltration of inflammatory cells, epithelial-to-mesenchymal transition (EMT), and renal tubulointer...