Towards Development of a Non-Toxigenic <i>Clostridioides difficile</i> Oral Spore Vaccine against Toxigenic <i>C. difficile</i>
<i>Clostridioides difficile</i> is an opportunistic gut pathogen which causes severe colitis, leading to significant morbidity and mortality due to its toxins, TcdA and TcdB. Two intra-muscular toxoid vaccines entered Phase III trials and strongly induced toxin-neutralising antibodies sy...
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MDPI AG,
2022-05-01T00:00:00Z.
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