Defective Toll-Like Receptors Driven B Cell Response in Hyper IgE Syndrome Patients With STAT3 Mutations

Autosomal dominant hyper-IgE syndrome (AD-HIES) is a rare inherited primary immunodeficient disease (PIDs), which is caused by STAT3 gene mutations. Previous studies indicated a defective Toll-like receptor (TLR) 9-induced B cell response in AD-HIES patients, including proliferation, and IgG product...

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Main Authors: Ruolan Gong (Author), Jing Wu (Author), Yingying Jin (Author), Tongxin Chen (Author)
Format: Book
Published: Frontiers Media S.A., 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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