Development of a Discriminative Dissolution Method, Using In-Silico Tool for Hydrochlorothiazide and Valsartan Tablets

Development of a Discriminative Dissolution Method, Using In-Silico Tool for Hydrochlorothiazide and Valsartan Tablets

Hydrochlorothiazide (HTZ) and Valsartan (VAL) are poorly soluble drugs in BCS classes IV and II. This study aimed to develop a method to assess the dissolution profile of tablets containing HTZ (12.5 mg) and VAL (160 mg) as a fixed-dose combination, using in silico tools to evaluate products markete...

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Main Authors: Rosmery Merma Leon (Author), Michele Georges Issa (Author), Marcelo Dutra Duque (Author), Josiane Souza Pereira Daniel (Author), Humberto Gomes Ferraz (Author)
Format: Book
Published: MDPI AG, 2023-06-01T00:00:00Z.
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