The prognostic significance of p16 expression pattern in diffuse gliomas

• Main Authors: Jin Woo Park (Author), Jeongwan Kang (Author), Ka Young Lim (Author), Hyunhee Kim (Author), Seong-Ik Kim (Author), Jae Kyung Won (Author), Chul-Kee Park (Author), Sung-Hye Park (Author)
• Format: Book
• Published: Korean Society of Pathologists & the Korean Society for Cytopathology, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background CDKN2A is a tumor suppressor gene that encodes the cell cycle inhibitor protein p16. Homozygous deletion of the CDK-N2A gene has been associated with shortened survival in isocitrate dehydrogenase (IDH)-mutant gliomas. This study aimed to analyze the prognostic value of p16 and to evaluat...