Natural-source payloads used in the conjugated drugs architecture for cancer therapy: Recent advances and future directions

• Main Authors: Cuiping Li (Author), Kourong Shi (Author), Siyuan Zhao (Author), Juan Liu (Author), Qiaoli Zhai (Author), Xiaoli Hou (Author), Jie Xu (Author), Xinyu Wang (Author), Jiahui Liu (Author), Xin Wu (Author), Wei Fan (Author)
• Format: Book
• Published: Elsevier, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug conjugates are obtained from tumor-located vectors connected to cytotoxic agents via linkers, which are designed to deliver hyper-toxic payloads directly to targeted cancer cells. These drug conjugates include antibody-drug conjugates (ADCs), peptide-drug conjugates (PDCs), small molecule-drug...