Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

Functional Rescue of a Nephrogenic Diabetes Insipidus Causing Mutation in the V2 Vasopressin Receptor by Specific Antagonist and Agonist Pharmacochaperones

The urine concentrating function of the kidney is essential to maintain the water homeostasis of the human body. It is mainly regulated by the arginine-vasopressin (AVP), which targets the type 2 vasopressin receptor (V2R) in the kidney. The inability of V2R to respond to AVP stimulation leads to de...

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Main Authors: Laura Szalai (Author), András Sziráki (Author), László Sándor Erdélyi (Author), Kinga Bernadett Kovács (Author), Miklós Tóth (Author), András Dávid Tóth (Author), Gábor Turu (Author), Dominique Bonnet (Author), Bernard Mouillac (Author), László Hunyady (Author), András Balla (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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