Bacterial Lectin FimH and Its Aggregation Hot-Spots: An Alternative Strategy against Uropathogenic <i>Escherichia coli</i>

• Main Authors: Georgia I. Nasi (Author), Konstantina I. Georgakopoulou (Author), Marilena K. Theodoropoulou (Author), Nikos C. Papandreou (Author), Evangelia D. Chrysina (Author), Paraskevi L. Tsiolaki (Author), Vassiliki A. Iconomidou (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type I fimbriae are the main adhesive organelles of uropathogenic <i>Escherichia coli</i> (UPEC), consisting of four different subunits. Their component with the most important role in establishing bacterial infections is the FimH adhesin located at the fimbrial tip. This two-domain prot...