HNRNPC promotes collagen fiber alignment and immune evasion in breast cancer via activation of the VIRMA-mediated TFAP2A/DDR1 axis

• المؤلفون الرئيسيون: Bin Lian (مؤلف), Shuxun Yan (مؤلف), Jiayi Li (مؤلف), Zhengyang Bai (مؤلف), Jinping Li (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2023-08-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Cancers aggressively reorganize collagen in their microenvironment, leading to the evasion of tumor cells from immune surveillance. However, the biological significance and molecular mechanism of collagen alignment in breast cancer (BC) have not been well established. Methods In...