Ameliorative effects of umbelliferone against acetaminophen-induced hepatic oxidative stress and inflammation in mice

• Main Authors: Saeed Sadeghinejad (Author), Mehrnoosh Mousavi (Author), Leila Zeidooni (Author), Esrafil Mansouri (Author), Shokooh Mohtadi (Author), Mohammad Javad Khodayar (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and purpose: Acetaminophen (APAP) is a commonly used antipyretic and pain reliever that its overdose causes acute liver toxicity. Umbelliferone (UMB) has many pharmacological effects. In this study, the hepatoprotective effect of UMB on acute hepatotoxicity induced by APAP was investigate...