A Role of Intestinal Alkaline Phosphatase 3 (Akp3) in Inorganic Phosphate Homeostasis

• Main Authors: Shohei Sasaki (Author), Hiroko Segawa (Author), Ai Hanazaki (Author), Ruri Kirino (Author), Toru Fujii (Author), Kayo Ikuta (Author), Miwa Noguchi (Author), Sumire Sasaki (Author), Megumi Koike (Author), Kazuya Tanifuji (Author), Yuji Shiozaki (Author), Ichiro Kaneko (Author), Sawako Tatsumi (Author), Takaaki Shimohata (Author), Yoshichika Kawai (Author), Sonoko Narisawa (Author), José Luis Millán (Author), Ken-ichi Miyamoto (Author)
• Format: Book
• Published: Karger Publishers, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/Aims: Hyperphosphatemia is a serious complication of late-stage chronic kidney disease (CKD). Intestinal inorganic phosphate (Pi) handling plays an important role in Pi homeostasis in CKD. We investigated whether intestinal alkaline phosphatase 3 (Akp3), the enzyme that hydrolyzes dietary...