Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh.

• Main Authors: Aklima Akter (Author), Pinki Dash (Author), Amena Aktar (Author), Sultana Rownok Jahan (Author), Sadia Afrin (Author), Salima Raiyan Basher (Author), Al Hakim (Author), Asura Khanam Lisa (Author), Fahima Chowdhury (Author), Ashraful I Khan (Author), Peng Xu (Author), Richelle C Charles (Author), Meagan Kelly (Author), Pavol Kováč (Author), Jason B Harris (Author), Taufiqur Rahman Bhuiyan (Author), Stephen B Calderwood (Author), Edward T Ryan (Author), Firdausi Qadri (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>Oral cholera vaccine (OCV) containing killed Vibrio cholerae O1 and O139 organisms (Bivalent-OCV; Biv-OCV) are playing a central role in global cholera control strategies. OCV is currently administered in a 2-dose regimen (day 0 and 14). There is a growing body of evid...