A Soft Skin Adhesive (SSA) Patch for Extended Release of Pirfenidone in Burn Wounds

• Main Authors: Eugene P. Chung (Author), Jesse Q. Nguyen (Author), Tobias Tellkamp-Schehr (Author), Katja Goebel (Author), Anita Ollek (Author), Cliff Krein (Author), Adrienne R. Wells (Author), Eliza A. Sebastian (Author), Anja Goebel (Author), Svenja Niese (Author), Kai P. Leung (Author)
• 格式: 圖書
• 出版: MDPI AG, 2023-06-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

As much as half or more of deep partial-thickness burn wounds develop hypertrophic scarring and contracture. Once formed, treatments are only minimally effective. Pirfenidone (Pf), indicated for treatment of idiopathic pulmonary fibrosis, is an anti-inflammatory and anti-fibrotic small molecule that...