Investigation of magnesium aluminometasilicate (Neusilin US2) based surface solid dispersion of sorafenib tosylate using QbD approach: In vitro and in vivo pharmacokinetic study

Background and purpose: Sorafenib tosylate (SFN), a potent multikinase inhibitor, is used for the treatment of various cancers. However, it shows limited therapeutic applications due to its poor biopharmaceutical properties. The aim of the present investigation is to develop surface solid dispersion...

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Main Authors: Bijoy Kumar Panda (Author), Bothiraja Chellampillai (Author), Sharad Ghodke (Author), Ashwin Mali (Author), Ravindra Kamble (Author)
Format: Book
Published: International Association of Physical Chemists (IAPC), 2024-08-01T00:00:00Z.
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