Genetic and epigenetic modifications induced by chemotherapeutic drugs: human amniotic fluid stem cells as an in-vitro model

• Main Authors: Prabin Upadhyaya (Author), Alessandra Di Serafino (Author), Luca Sorino (Author), Patrizia Ballerini (Author), Marco Marchisio (Author), Laura Pierdomenico (Author), Liborio Stuppia (Author), Ivana Antonucci (Author)
• Format: Book
• Published: BMC, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Bleomycin, etoposide and cisplatin (BEP) are three chemotherapeutic agents widely used individually or in combination with each other or other chemotherapeutic agents in the treatment of various cancers. These chemotherapeutic agents are cytotoxic; hence, along with killing cance...