Cytotoxicity of the methanol extracts and compounds of Brucea antidysenterica (Simaroubaceae) towards multifactorial drug-resistant human cancer cell lines

• Main Authors: Laetitia M. Youmbi (Author), Yves S. D. Makong (Author), Armelle T. Mbaveng (Author), Simplice B. Tankeo (Author), Ghislain W. Fotso (Author), Bruno L. Ndjakou (Author), Jean D. Wansi (Author), Veronique P. Beng (Author), Norbert Sewald (Author), Bonaventure T. Ngadjui (Author), Thomas Efferth (Author), Victor Kuete (Author)
• Format: Book
• Published: BMC, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Cancer remains a global health concern and constitutes an important barrier to increasing life expectancy. Malignant cells rapidly develop drug resistance leading to many clinical therapeutic failures. The importance of medicinal plants as an alternative to classical drug discove...