Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling

Teriflunomide Is an Indirect Human Constitutive Androstane Receptor (CAR) Activator Interacting With Epidermal Growth Factor (EGF) Signaling

The constitutive androstane receptor (CAR) is a nuclear receptor involved mainly in xenobiotic and endobiotic metabolism regulation. CAR is activated directly by its ligands via the ligand binding domain (LBD) or indirectly by inhibition of the epidermal growth factor (EGF) signaling. We found that...

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Main Authors: Alejandro Carazo (Author), Jan Dusek (Author), Ondrej Holas (Author), Josef Skoda (Author), Lucie Hyrsova (Author), Tomas Smutny (Author), Tomas Soukup (Author), Martin Dosedel (Author), Petr Pávek (Author)
Format: Book
Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
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3rd Floor Main Library

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