Polyfunctionalized α-Phenyl-tert-butyl(benzyl)nitrones: Multifunctional Antioxidants for Stroke Treatment

• Main Authors: Daniel Diez-Iriepa (Author), Damijan Knez (Author), Stanislav Gobec (Author), Isabel Iriepa (Author), Cristóbal de los Ríos (Author), Isaac Bravo (Author), Francisco López-Muñoz (Author), José Marco-Contelles (Author), Dimitra Hadjipavlou-Litina (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nowadays, most stroke patients are treated exclusively with recombinant tissue plasminogen activator, a drug with serious side effects and limited therapeutic window. For this reason, and because of the known effects of oxidative stress on stroke, a more tolerable and efficient therapy for stroke is...