Administration of pilocarpine by microneedle patch as a novel method for cystic fibrosis sweat testing

• Main Authors: Song Li (Author), Kelsey Hart (Author), Natalie Norton (Author), Clare A. Ryan (Author), Lokesh Guglani (Author), Mark R. Prausnitz (Author)
• Format: Book
• Published: Wiley, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The sweat test is the gold standard for the diagnosis of cystic fibrosis (CF). The test utilizes iontophoresis to administer pilocarpine to the skin to induce sweating for measurement of chloride concentration in sweat. However, the sweat test procedure needs to be conducted in an accredite...