EXP2SL: A Machine Learning Framework for Cell-Line-Specific Synthetic Lethality Prediction

Synthetic lethality (SL), an important type of genetic interaction, can provide useful insight into the target identification process for the development of anticancer therapeutics. Although several well-established SL gene pairs have been verified to be conserved in humans, most SL interactions rem...

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Main Authors: Fangping Wan (Author), Shuya Li (Author), Tingzhong Tian (Author), Yipin Lei (Author), Dan Zhao (Author), Jianyang Zeng (Author)
Format: Book
Published: Frontiers Media S.A., 2020-02-01T00:00:00Z.
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