Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors

• Glavni autori: Zainab M. Elsayed (Autor), Hadia Almahli (Autor), Alessio Nocentini (Autor), Andrea Ammara (Autor), Claudiu T. Supuran (Autor), Wagdy M. Eldehna (Autor), Sahar M. Abou-Seri (Autor)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

As part of our ongoing endeavour to identify novel inhibitors of cancer-associated CA isoforms IX and XII as possible anticancer candidates, here we describe the design and synthesis of small library of 2-aryl-quinazolin-4-yl aminobenzoic acid derivatives (6a-c, 7a-c, and 8a-c) as new non-classical...