Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors

• Main Authors: Zainab M. Elsayed (Author), Hadia Almahli (Author), Alessio Nocentini (Author), Andrea Ammara (Author), Claudiu T. Supuran (Author), Wagdy M. Eldehna (Author), Sahar M. Abou-Seri (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

As part of our ongoing endeavour to identify novel inhibitors of cancer-associated CA isoforms IX and XII as possible anticancer candidates, here we describe the design and synthesis of small library of 2-aryl-quinazolin-4-yl aminobenzoic acid derivatives (6a-c, 7a-c, and 8a-c) as new non-classical...