High vs. Low Initial Oxygen to Improve the Breathing Effort of Preterm Infants at Birth: Study Protocol for a Randomized Controlled Trial

• Main Authors: Janneke Dekker (Author), Stuart B. Hooper (Author), Martin Giera (Author), Erin V. McGillick (Author), G. Jeroen Hutten (Author), W. Onland (Author), Anton H. van Kaam (Author), Arjan B. te Pas (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Although most preterm infants breathe at birth, their respiratory drive is weak and supplemental oxygen is often needed to overcome hypoxia. This could in turn lead to hyperoxia. To reduce the risk of hyperoxia, currently an initial low oxygen concentration (21-30%) is recommended during...