Cysteine proteases as digestive enzymes in parasitic helminths.

• Main Authors: Conor R Caffrey (Author), Louise Goupil (Author), Karina M Rebello (Author), John P Dalton (Author), David Smith (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We briefly review cysteine proteases (orthologs of mammalian cathepsins B, L, F, and C) that are expressed in flatworm and nematode parasites. Emphasis is placed on enzyme activities that have been functionally characterized, are associated with the parasite gut, and putatively contribute to degradi...