Inactivation of Ras and Changes of Mitochondrial Membrane Potential Contribute to Oridonin-Induced Autophagy in A431 Cells

• Главные авторы: Dan Li (Автор), Qiao Cui (Автор), Shen-geng Chen (Автор), Li-jun Wu (Автор), Shin-ichi Tashiro (Автор), Satoshi Onodera (Автор), Takashi Ikejima (Автор)
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• Опубликовано: Elsevier, 2007-01-01T00:00:00Z.
• Предметы: article
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We have previously shown that oridonin isolated from Rabdosia rubescens augmented apoptosis while inhibiting autophagy within 24 h in HeLa cells. However, the mechanisms between apoptosis and autophagy induced by oridonin in A431 cells are largely unknown. Here, it was found that autophagic level is...