Molecular profile of pure squamous cell carcinoma of the bladder identifies major roles for OSMR and YAP signalling

• Main Authors: Carolyn D Hurst (Author), Guo Cheng (Author), Fiona M Platt (Author), Olivia Alder (Author), Emma VI Black (Author), Julie E Burns (Author), Joanne Brown (Author), Sunjay Jain (Author), Jo‐An Roulson (Author), Margaret A Knowles (Author)
• Format: Book
• Published: Wiley, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Pure squamous cell carcinoma (SCC) is the most common pure variant form of bladder cancer, found in 2-5% of cases. It often presents late and is unresponsive to cisplatin‐based chemotherapy. The molecular features of these tumours have not been elucidated in detail. We carried out whole‐exo...