Targeting Liver <i>Xor</i> by GalNAc-siRNA Is an Effective Strategy for Hyperuricemia Therapy

• Príomhchruthaitheoirí: Huiyan Sun (Údar), Xinxia Wang (Údar), Yongqiang Li (Údar), Yingzhi Shen (Údar), Lin Zhang (Údar), Yingjie Xu (Údar), Junling Liu (Údar), Xuemei Fan (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: MDPI AG, 2024-07-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Hyperuricemia, i.e., increased plasma uric acid concentration, is a common problem in clinical practice, leading to gout or nephrolithiasis, and is associated with other disorders, such as metabolic syndrome, cardiovascular disease, and chronic renal disease. Xanthine oxidoreductase (XOR) is a criti...