Obesity and Low-Grade Inflammation Increase Plasma Follistatin-Like 3 in Humans

• Main Authors: Claus Brandt (Author), Maria Pedersen (Author), Anders Rinnov (Author), Anne S. Andreasen (Author), Kirsten Møller (Author), Pernille Hojman (Author), Bente K. Pedersen (Author), Peter Plomgaard (Author)
• Format: Book
• Published: Hindawi Limited, 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Rodent models suggest that follistatin-like 3 (fstl3) is associated with diabetes and obesity. In humans, plasma fstl3 is reduced with gestational diabetes. In vitro, TNF-α induces fstl3 secretion, which suggests a link to inflammation. Objective. To elucidate the association between pla...